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Nap of Youth | Organoid Farm | Walnut Paradox
Issue #224
My birthday was this week and I like sharing it, so HAPPY BIRTHDAY!
We’re looking back at my favorite age-inspired science news. If you forgot to get me a gift, just forward this to your friends!
—Steve 🥳
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Steve made this with chatGPT
Nap of Youth
There is no fountain of youth, but there are dwarf lemurs. Researchers found how the sleepy primates slow down cellular aging while hibernating.
Hibernates up to 7 months per year
Lowering heart rate by 96% and breathing ~6x per hour
Reduces oxidative stress and elongates telomeres
Telomeres, the protective caps at chromosome tips, gradually shorten with age as cells divide. Further research could improve our understanding of human aging and organ preservation. Or at least let us catch some Zs.
Sweet dreamzzz - see a baby lemur…and more details
Organoid Farm
Bespoke drug testing is here. Scientists developed a faster way to create organoids for RNA treatment tests.
Organoid = tiny tissue structures grown from patient cells
Can predict drug effectiveness for specific patients
New method saves up to ~1 year of growth time
Over 300 patients have been tested, focusing on RNA-based approaches for rare diseases. Treatments still have to undergo animal testing for safety, but further studies could reduce approval timelines. And maybe help me regrow a spleen!
Future health insurance - personalized organoid banks
Walnut Paradox
Sea walnuts can age in reverse. Also known as Mnemiopsis leidyi, the comb jellyfish revert to a larval stage under stress.
Shrink and revive when stressed
Born-again walnuts grow larval tentacles to catch food
Retain cellular identity throughout age-traversal
This is likely how M. leidyi survived stowing away in ships to become an invasive species in parts of Europe and Asia. Sea walnuts join immortal jellyfish and a tapeworm species on the short list of known age-travelling organisms. “Benjamin Button” of the sea.
Back when I was older - learn more about ocean walnuts

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Clickables
🏁 Best monochromatic photos of 2025 (the whale eye 👀)
🔭 Gaze beyond the stars w/ astronomy photos of the year
⚡️ Transforming toxic mud into ceramics w/ “lightning”
🐠 Listen up! — FishEye’s ironic library of fish sounds
🧑🚀 Clickbait: I applied to be an astronaut, this is what NASA said

Unnatural Selection
Last week: “Do you like pineapples on pizza?”

Steve made this with Procreate
One of these days I’ll find a way to ask y’all if a hotdog is a sandwich. 😅
I’m debating keeping this section active. I need more weekly votes to make silly pie charts. Please vote on this week’s poll below!
Hmm…You’re a lemur! How will you catch 7 months of Zs? |

st3v on site
Say “Kaas”!
Throwback to last year’s birthday week! I don’t speak Dutch, but I’m pretty sure this tardigrade was saying “Happy Birthday!”.

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